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coxsackievirus-b
Coxsackievirus B
Non-enveloped +ssRNA enterovirus (Picornaviridae), 6 serotypes. Leading infectious cause of acute myocarditis; major antecedent of dilated cardiomyopathy. Replicates cytolytically in cardiomyocytes via CAR; protease 2A cleaves dystrophin.
Entry Metadata
| Field | Value |
|---|---|
| ID | coxsackievirus-b |
| Name | Coxsackievirus B |
| Status | draft |
| Last reviewed | 2026-06-03 |
| Class | 01-viruses |
Cross-Atlas Connections
Sources
- Cooper LT Jr. Myocarditis. N Engl J Med. 2009;360(15):1526-38. · PubMed 19357408
- Kindermann I, Barth C, Mahfoud F, et al. Update on myocarditis. J Am Coll Cardiol. 2012;59(9):779-92. · PubMed 22361396
- Rose NR. Viral myocarditis. Curr Opin Rheumatol. 2016;28(4):383-9. · PubMed 27166925
- NCBI Taxonomy — Enterovirus B, species; Coxsackievirus B1-B6, serotypes.
- Yang D, Itagaki M, Buja LM, Garg NJ. Coxsackievirus B3 replication, apoptosis, and persistence in the heart. Cell Microbiol. 2009;11(11):1658-71. · PubMed 19575749