Atlas One · Host Biology · Scale 06 — Organ

Microcephaly

Head circumference >2–3 SD below mean for age/sex; reflects reduced brain volume from impaired neuroprogenitor proliferation. Causes: congenital infections (Zika, CMV, rubella), genetic mutations (ASPM, CDK5RAP2), metabolic disorders. Prognosis varies by etiology and severity.

Also known as: primary microcephaly, secondary microcephaly, microcephalic primordial dwarfism

Scale 06 — OrganScale
draftStatus
2026-06-06Last Reviewed
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microcephaly

Microcephaly

Head circumference >2–3 SD below mean for age/sex; reflects reduced brain volume from impaired neuroprogenitor proliferation. Causes: congenital infections (Zika, CMV, rubella), genetic mutations (ASPM, CDK5RAP2), metabolic disorders. Prognosis varies by etiology and severity.

Entry Metadata

FieldValue
IDmicrocephaly
NameMicrocephaly
Statusdraft
Last reviewed2026-06-06
Atlas01-human
Scale06-organ

Cross-Atlas Connections

targetsBrain part-ofNervous System connects-toPlacenta connects-toAicardi Goutieres Syndrome connects-toAedes Aegypti

Sources