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mmr-vaccine
MMR Vaccine (M-M-R II / Priorix)
Live-attenuated measles-mumps-rubella vaccine. Two-dose schedule achieves >97% seroconversion; 95% coverage required for measles herd immunity. Wakefield 1998 paper (retracted 2010) falsely linked MMR to autism — refuted by >15 large cohort studies.
Entry Metadata
| Field | Value |
|---|---|
| ID | mmr-vaccine |
| Name | MMR Vaccine (M-M-R II / Priorix) |
| Status | active |
| Last reviewed | 2026-06-06 |
| Platform | 05 — Live-Attenuated |
| Delivery system | lyophilized live attenuated viruses |
| Adjuvants | None |
| Route | subcutaneous |
| Dose schedule | Dose 1: 12–15 months; Dose 2: 4–6 years. Minimum interval: 4 weeks between doses. |
| Manufacturer | Merck (M-M-R II); GSK (Priorix); Serum Institute of India (Tresivac); sanofi (discontinued) |
| Cold chain | 2–8°C (in dark); reconstituted vaccine must be used within 8 hours; discard unused reconstituted vaccine |
Cross-Atlas Connections
Sources
- Madsen KM, Hviid A, Vestergaard M, et al. A Population-Based Study of Measles, Mumps, and Rubella Vaccination and Autism. N Engl J Med. 2002;347(19):1477-1482. · PubMed 12421889
- Hviid A, Hansen JV, Frisch M, Melbye M. Measles, Mumps, Rubella Vaccination and Autism: A Nationwide Cohort Study. Ann Intern Med. 2019;170(8):513-520. · PubMed 30831578
- Wakefield AJ, et al. Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet. 1998;351(9103):637-641. RETRACTED February 2010.
- Demicheli V, Rivetti A, Debalini MG, Di Pietrantonj C. Vaccines for measles, mumps and rubella in children. Cochrane Database Syst Rev. 2012;2:CD004407. · PubMed 22336803
- World Health Organization. Global Measles and Rubella: Strategic Plan 2012–2020. Geneva: WHO; 2012.