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bradykinin
Bradykinin
Bradykinin is a kallikrein-generated nonapeptide; B2 receptor → eNOS → NO and PGI2 → vasodilation; ACE degrades bradykinin — ACE inhibition causes cough and angioedema; hereditary angioedema (C1-INH deficiency) is treated with icatibant (B2R antagonist) or lanadelumab.
Entry Metadata
| Field | Value |
|---|---|
| ID | bradykinin |
| Name | Bradykinin |
| Status | draft |
| Last reviewed | 2026-06-07 |
| Atlas | 01-human |
| Scale | 03-molecular |