MedForge / Apps / Endocrine Axes
Endocrine · Feedback simulator
Endocrine Axes
Force a hormone. Predict the loop.
Hormone axes from thyroid to prolactin, each with cases to predict. A lesion or a drug forces one hormone high or low. Predict what the feedback does to the rest, then see why and choose the next test and the treatment principle.
Free preview: explore the thyroid and adrenal axes and play the first six cases. Unlock the full library. $2.99/month or $19.99/year
Live demo of Endocrine Axes
Try it: predict the loop
Pick a case, set each hormone to low, normal or high, then check. The loop animates the answer.
In the app
A real screen from Endocrine Axes
From the iPhone app, in a pre-release build. The Android app follows the same design, and the text size can be changed from 40% to 300% on every screen.
Sources
Every fact in this app is cited
These are the references this app draws on. Inside the app, each answer links to its source in a reading window that keeps your place.
- HyperthyroidismAmerican Thyroid Association · American Thyroid Association
- ThyroiditisAmerican Thyroid Association · American Thyroid Association
- AcromegalyNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Adrenocorticotropic Hormone (ACTH) TestNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Addison DiseaseNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Anabolic SteroidsNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Calcium blood testNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- C-Peptide TestNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Cushing SyndromeNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Cushing syndromeNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Diabetes insipidusNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Ectopic Cushing syndromeNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Growth hormone suppression testNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Growth Hormone TestsNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Graves diseaseNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Growth DisordersNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- HyperparathyroidismNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- HyperthyroidismNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- HypoglycemiaNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Low blood sodiumNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- HypopituitarismNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- HypoparathyroidismNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- HypothyroidismNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Kallmann syndromeNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Klinefelter syndromeNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Laron syndromeNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Ovarian DisordersNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Pituitary TumorNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Primary and secondary hyperaldosteronismNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Prolactin LevelsNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Prolactin blood testNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Parathyroid Hormone (PTH) TestNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Renin TestNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Syndrome of inappropriate antidiuretic hormone secretionNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Type 1 DiabetesNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Testosterone Levels TestNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- TSH (Thyroid-Stimulating Hormone) TestNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Vitamin DNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Vitamin D TestNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- AcromegalyNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH · NIDDK / NIH
- Adrenal Insufficiency & Addison's DiseaseNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH · NIDDK / NIH
- Cushing's SyndromeNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH · NIDDK / NIH
- Diabetes InsipidusNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH · NIDDK / NIH
- Graves' DiseaseNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH · NIDDK / NIH
- Primary HyperparathyroidismNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH · NIDDK / NIH
- Low Blood Glucose (Hypoglycemia)National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH · NIDDK / NIH
- Hypothyroidism (Underactive Thyroid)National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH · NIDDK / NIH
- Type 1 DiabetesNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH · NIDDK / NIH
- Type 2 DiabetesNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH · NIDDK / NIH
- Hyperparathyroidism (primary): diagnosis, assessment and initial management (NG132)National Institute for Health and Care Excellence (NICE) · NICE (UK)
- Thyroid disease: assessment and management (NG145)National Institute for Health and Care Excellence (NICE) · NICE (UK)
- Type 1 diabetes in adults: diagnosis and management (NG17)National Institute for Health and Care Excellence (NICE) · NICE (UK)
- Menopause: identification and management (NG23)National Institute for Health and Care Excellence (NICE) · NICE (UK)
- Type 2 diabetes in adults: management (NG28)National Institute for Health and Care Excellence (NICE) · NICE (UK)
- Electrolyte BalanceOpenStax, Rice University · OpenStax (Rice University)
- The Pituitary Gland and HypothalamusOpenStax, Rice University · OpenStax (Rice University)
- The Thyroid GlandOpenStax, Rice University · OpenStax (Rice University)
- The Parathyroid GlandsOpenStax, Rice University · OpenStax (Rice University)
- The Adrenal GlandsOpenStax, Rice University · OpenStax (Rice University)
- Gonadal and Placental HormonesOpenStax, Rice University · OpenStax (Rice University)
- The Endocrine PancreasOpenStax, Rice University · OpenStax (Rice University)
- AcromegalyStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Physiology, Adrenocorticotropic Hormone (ACTH)StatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Adrenal InsufficiencyStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Anabolic SteroidsStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Physiology, CortisolStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Hypercortisolism (Cushing Syndrome)StatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Cushing DiseaseStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Arginine Vasopressin Disorder (Diabetes Insipidus)StatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Factitious HypoglycemiaStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Physiology, Gonadotropin-Releasing HormoneStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Graves DiseaseStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- HyperaldosteronismStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- HyperprolactinemiaStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Primary HyperparathyroidismStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- HypoaldosteronismStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- HypocalcemiaStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- HyponatremiaStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- HypopituitarismStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- HypoparathyroidismStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- HypothyroidismStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Biochemistry, Insulin Metabolic EffectsStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Insulin ResistanceStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- InsulinomaStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Kallmann SyndromeStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Klinefelter SyndromeStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- LevothyroxineStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Male HypogonadismStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Physiology, Pituitary GlandStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Primary Ovarian InsufficiencyStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Primary PolydipsiaStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Physiology, ProlactinStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- ProlactinomaStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Physiology, Parathyroid HormoneStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Physiology, Renin Angiotensin SystemStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Renal Artery StenosisStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Secondary HyperparathyroidismStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Syndrome of Inappropriate Antidiuretic Hormone SecretionStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Type 1 DiabetesStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Laboratory Assessment of Thyroid FunctionStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Physiology, Thyroid HormoneStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- ThyrotoxicosisStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Physiology, VasopressinStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Vitamin D DeficiencyStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Diabetes (fact sheet)World Health Organization · WHO
- Vitamin B12 deficiency anemia (MedlinePlus Medical Encyclopedia)National Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management (CG184)National Institute for Health and Care Excellence (NICE) · NICE (UK)
- 23.4 The StomachOpenStax, Rice University (peer-reviewed open textbook) · OpenStax (Rice University)
- Physiology, GastrinStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Pernicious AnemiaStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Proton Pump Inhibitors (PPI)StatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Physiology, StomachStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Aldosterone TestNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Amiodarone: drug informationNational Library of Medicine, MedlinePlus · NIH / NLM MedlinePlus
- Polycythemia vera (MedlinePlus Medical Encyclopedia)MedlinePlus Medical Encyclopedia, National Library of Medicine · NIH / NLM MedlinePlus
- 21-hydroxylase deficiency (MedlinePlus Genetics)MedlinePlus Genetics, National Library of Medicine · NIH / NLM MedlinePlus
- Polycythemia vera (MedlinePlus Genetics)MedlinePlus Genetics, National Library of Medicine · NIH / NLM MedlinePlus
- Turner syndrome (MedlinePlus Genetics)MedlinePlus Genetics, National Library of Medicine · NIH / NLM MedlinePlus
- X-linked hypophosphatemia (MedlinePlus Genetics)MedlinePlus Genetics, National Library of Medicine · NIH / NLM MedlinePlus
- Anemia in Chronic Kidney DiseaseNIDDK, National Institutes of Health · NIDDK / NIH
- Gastritis and GastropathyNIDDK, National Institutes of Health · NIDDK / NIH
- Zollinger-Ellison SyndromeNIDDK, National Institutes of Health · NIDDK / NIH
- Regulation of Proximal Tubule Phosphate Transport: New Partners, New PathwaysPubMed Central · Peer-reviewed review (PMC)
- Physiology, PhosphateStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- 18.3 Erythrocytes (Anatomy and Physiology 2e)OpenStax, Rice University · OpenStax (Rice University)
- Water BalanceOpenStax, Rice University (peer-reviewed open textbook) · OpenStax (Rice University)
- Amiodarone and thyroid physiology, pathophysiology, diagnosis and managementTrends in Cardiovascular Medicine (PubMed Central) · Peer-reviewed review (PMC)
- Future Directions in the Management of Classic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase DeficiencyJournal of Clinical Endocrinology and Metabolism (PubMed Central) · Peer-reviewed review (PMC)
- Neuroendocrine disturbances in women with functional hypothalamic amenorrhea: an update and future directionsEndocrine (PubMed Central) · Peer-reviewed review (PMC)
- Neural, hormonal, and paracrine regulation of gastrin and acid secretionYale Journal of Biology and Medicine (PubMed Central) · Peer-reviewed review (PMC)
- Pituitary gigantism: update on molecular biology and managementCurrent Opinion in Endocrinology, Diabetes and Obesity (PubMed Central) · Peer-reviewed review (PMC)
- Approach to Hypophosphatemic RicketsJournal of Clinical Endocrinology and Metabolism (PubMed Central) · Peer-reviewed review (PMC)
- Latent autoimmune diabetes in adults: a focus on beta-cell protection and therapyFrontiers in Endocrinology (PubMed Central) · Peer-reviewed review (PMC)
- Approach to the Patient: ReninomaJournal of Clinical Endocrinology and Metabolism (PubMed Central) · Peer-reviewed review (PMC)
- ACE InhibitorsStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Physiology, AldosteroneStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- AmiodaroneStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Anemia of Chronic Kidney DiseaseStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Congenital Adrenal HyperplasiaStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- De Quervain ThyroiditisStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- GastrinomaStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- HyperthyroidismStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- HypophosphatemiaStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Pituitary AdenomaStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Polycythemia VeraStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Secondary PolycythemiaStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Sheehan SyndromeStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- SulfonylureasStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Turner SyndromeStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Vitamin D ToxicityStatPearls Publishing, National Library of Medicine (NCBI Bookshelf) · NIH / NLM
- Emergency interventions for hyperkalaemiaCochrane Database Syst Rev 2005 (via PubMed Central) · Cochrane review (PMC)