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acetylcholine
Acetylcholine
Quaternary ammonium ester (MW 182.65) synthesised by ChAT from acetyl-CoA + choline. Activates nicotinic (ionotropic) and muscarinic (GPCR) receptors at NMJ, autonomic ganglia, and CNS. AChE hydrolysis terminates signal in <1 ms. Deficiency underlies Alzheimer's disease.
Entry Metadata
| Field | Value |
|---|---|
| ID | acetylcholine |
| Name | Acetylcholine |
| Status | draft |
| Last reviewed | 2026-06-05 |
| Atlas | 01-human |
| Scale | 03-molecular |