Atlas One · Host Biology · Scale 03 — Molecular

CD30

CD30 (TNFRSF8) is a TNF receptor family member expressed on Reed-Sternberg cells (~100% cHL), ALCL (~100%), and activated lymphocytes; CD30L → TRAF2/5 → NF-κB; brentuximab vedotin (anti-CD30 ADC, MMAE) is the principal CD30-targeting therapy across cHL, ALCL, and CD30+ PTCL.

Also known as: CD30, TNFRSF8, Ki-1 antigen, CD30 lymphoma, CD30 Reed-Sternberg, brentuximab target, CD30 ALCL, CD30 Hodgkin lymphoma

Scale 03 — MolecularScale
draftStatus
2026-06-06Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
cd30

CD30

CD30 (TNFRSF8) is a TNF receptor family member expressed on Reed-Sternberg cells (~100% cHL), ALCL (~100%), and activated lymphocytes; CD30L → TRAF2/5 → NF-κB; brentuximab vedotin (anti-CD30 ADC, MMAE) is the principal CD30-targeting therapy across cHL, ALCL, and CD30+ PTCL.