Atlas One · Host Biology · Scale 07 — System

Hodgkin Lymphoma

Hodgkin lymphoma is a GC B cell-derived malignancy; RS cells ~100% CD30+; 9p24.1 amplification drives CD30+PD-L1/L2 co-expression; A+AVD (ECHELON-1) is standard for advanced stage; nivolumab/pembrolizumab for R/R; 5-year OS >85% overall; NLPHL has distinct CD20+ biology.

Also known as: Hodgkin lymphoma, HL, cHL, classical Hodgkin lymphoma, NLPHL, Reed-Sternberg, Hodgkin disease, nodular sclerosis HL, mixed cellularity HL

Scale 07 — SystemScale
draftStatus
2026-06-06Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
hodgkin-lymphoma

Hodgkin Lymphoma

Hodgkin lymphoma is a GC B cell-derived malignancy; RS cells ~100% CD30+; 9p24.1 amplification drives CD30+PD-L1/L2 co-expression; A+AVD (ECHELON-1) is standard for advanced stage; nivolumab/pembrolizumab for R/R; 5-year OS >85% overall; NLPHL has distinct CD20+ biology.

Entry Metadata

FieldValue
IDhodgkin-lymphoma
NameHodgkin Lymphoma
Statusdraft
Last reviewed2026-06-06
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toCd30 connects-toPd 1 connects-toNf Kb connects-toJak2 connects-toGerminal Center connects-toEpstein Barr Virus connects-toCd20 connects-toT Helper Cell connects-toSpleen connects-toLymphatic System connects-toDlbcl connects-toB Cell connects-toHiv Aids

Sources