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adiponectin
Adiponectin
Adiponectin is an adipokine paradoxically reduced in obesity; AdipoR1/AdipoR2 → AMPK and PPARα → insulin sensitization and fatty acid oxidation; low adiponectin drives NASH, T2D, and CVD; pioglitazone restores adiponectin and reduces NASH fibrosis.
Entry Metadata
| Field | Value |
|---|---|
| ID | adiponectin |
| Name | Adiponectin |
| Status | draft |
| Last reviewed | 2026-06-07 |
| Atlas | 01-human |
| Scale | 03-molecular |
Cross-Atlas Connections
Sources
- Kadowaki T, Yamauchi T. Adiponectin and adiponectin receptors. Endocr Rev. 2005;26(3):439-451. · PubMed 15897297
- Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem. 1995;270(45):26746-26749. · PubMed 7592907