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calcitonin
Calcitonin
Calcitonin is a 32-aa thyroid C-cell peptide that inhibits osteoclasts via CTR → cAMP → cytoskeletal collapse; salmon calcitonin treats Paget's disease and hypercalcemia; serum calcitonin is the primary biomarker for medullary thyroid carcinoma (MTC).
Entry Metadata
| Field | Value |
|---|---|
| ID | calcitonin |
| Name | Calcitonin |
| Status | draft |
| Last reviewed | 2026-06-07 |
| Atlas | 01-human |
| Scale | 03-molecular |
Cross-Atlas Connections
Sources
- Copp DH, Cameron EC, Cheney BA, Davidson AG, Henze KG. Evidence for calcitonin — a new hormone from the parathyroid that lowers blood calcium. Endocrinology. 1962;70:638-649. · PubMed 13881931
- Chesnut CH 3rd, Silverman S, Andriano K, et al. A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. Am J Med. 2000;109(4):267-276. · PubMed 10996576