Atlas One · Host Biology · Scale 03 — Molecular

LMP1

EBV LMP1 (latent membrane protein 1; 386 aa; 6 TM domains) mimics constitutively active CD40; CTAR1 → TRAF1/2/3 → NF-κB (alternative); CTAR2 → TRADD/TRAF6 → NF-κB (canonical); drives B cell immortalization, BCL-2, IL-6; oncogene in Hodgkin lymphoma and NPC.

Also known as: LMP1, latent membrane protein 1, LMP-1, EBV LMP1, BNLF1, EBV oncoprotein, constitutively active CD40, CTAR1, CTAR2, EBV immortalization, EBV NF-kB

Scale 03 — MolecularScale
draftStatus
2026-06-08Last Reviewed
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lmp1

LMP1

EBV LMP1 (latent membrane protein 1; 386 aa; 6 TM domains) mimics constitutively active CD40; CTAR1 → TRAF1/2/3 → NF-κB (alternative); CTAR2 → TRADD/TRAF6 → NF-κB (canonical); drives B cell immortalization, BCL-2, IL-6; oncogene in Hodgkin lymphoma and NPC.

Entry Metadata

FieldValue
IDlmp1
NameLMP1
Statusdraft
Last reviewed2026-06-08
Atlas01-human
Scale03-molecular

Cross-Atlas Connections

connects-toEpstein Barr Virus connects-toNf Kb connects-toP53 connects-toTgf Beta

Sources