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epstein-barr-virus
Epstein-Barr Virus
EBV (HHV-4; gammaherpesvirus; 172 kb dsDNA) infects >95% of adults; latency programs I/II/III expressing EBNA/LMP antigens drive oncogenesis; associated with Burkitt lymphoma, Hodgkin lymphoma, NPC, PTLD; infectious mononucleosis in adolescents; no approved vaccine or antiviral.
Entry Metadata
| Field | Value |
|---|---|
| ID | epstein-barr-virus |
| Name | Epstein-Barr Virus |
| Status | draft |
| Last reviewed | 2026-06-08 |
| Atlas | 01-human |
| Scale | 07-system |
Cross-Atlas Connections
Sources
- Cohen JI. Epstein-Barr virus infection. N Engl J Med. 2000;343(7):481-492. · PubMed 10944566
- Thorley-Lawson DA. Epstein-Barr virus: exploiting the immune system. Nat Rev Immunol. 2001;1(1):75-82. · PubMed 11905816
- Young LS, Rickinson AB. Epstein-Barr virus: 40 years on. Nat Rev Cancer. 2004;4(10):757-768. · PubMed 15510157