Atlas One · Host Biology · Scale 03 — Molecular

IL-23

IL-23 is a heterodimeric cytokine (IL-23p19/p40) produced by DCs and macrophages; IL-23 → IL-23R/JAK1/TYK2/STAT3 → Th17 cell maintenance and IL-17 production; IL-23 drives psoriasis and IBD; anti-IL-23p19 antibodies (risankizumab, guselkumab) are first-line biologics.

Also known as: IL-23, interleukin-23, IL-23p19, IL23A, IL-23/IL-17 axis, IL-23 cytokine, anti-IL-23, risankizumab target, Th17 cytokine, IL-23 IBD

Scale 03 — MolecularScale
draftStatus
2026-06-07Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
il-23

IL-23

IL-23 is a heterodimeric cytokine (IL-23p19/p40) produced by DCs and macrophages; IL-23 → IL-23R/JAK1/TYK2/STAT3 → Th17 cell maintenance and IL-17 production; IL-23 drives psoriasis and IBD; anti-IL-23p19 antibodies (risankizumab, guselkumab) are first-line biologics.

Entry Metadata

FieldValue
IDil-23
NameIL-23
Statusdraft
Last reviewed2026-06-07
Atlas01-human
Scale03-molecular

Cross-Atlas Connections

connects-toInflammatory Bowel Disease connects-toPsoriasis connects-toStat3 connects-toIl 6 connects-toIl 17A connects-toAnkylosing Spondylitis connects-toPsoriatic Arthritis connects-toT Helper Cell

Sources