Atlas One · Host Biology · Scale 03 — Molecular

CCR5

CCR5 (CC chemokine receptor 5; 7-TM GPCR) is the principal HIV-1 co-receptor for R5-tropic entry; CCL3/CCL4/CCL5 natural ligands; CCR5-Δ32 homozygosity → HIV-1 resistance; maraviroc (CCR5 antagonist) is the only approved HIV entry inhibitor; expressed on macrophages and T cells.

Also known as: CC chemokine receptor 5, CCR-5, CD195, RANTES receptor, CC-CKR-5, CKR-5, maraviroc target, HIV co-receptor

Scale 03 — MolecularScale
draftStatus
2026-06-08Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
ccr5

CCR5

CCR5 (CC chemokine receptor 5; 7-TM GPCR) is the principal HIV-1 co-receptor for R5-tropic entry; CCL3/CCL4/CCL5 natural ligands; CCR5-Δ32 homozygosity → HIV-1 resistance; maraviroc (CCR5 antagonist) is the only approved HIV entry inhibitor; expressed on macrophages and T cells.

Entry Metadata

FieldValue
IDccr5
NameCCR5
Statusdraft
Last reviewed2026-06-08
Atlas01-human
Scale03-molecular

Cross-Atlas Connections

connects-toHiv Aids expressed-byImmune System connects-toMultiple Sclerosis connects-toRheumatoid Arthritis

Sources