Atlas One · Host Biology · Scale 03 — Molecular

Norepinephrine

Catecholamine (MW 169.18), immediate Epi precursor and primary sympathetic postganglionic neurotransmitter. Activates α₁, α₂, β₁ adrenergic receptors. Locus coeruleus projects modulate CNS arousal. NET reuptake targeted by TCAs, SNRIs, cocaine, atomoxetine.

Also known as: noradrenaline, NE, NA, levarterenol, norepinephrinum

Scale 03 — MolecularScale
draftStatus
2026-06-05Last Reviewed
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norepinephrine

Norepinephrine

Catecholamine (MW 169.18), immediate Epi precursor and primary sympathetic postganglionic neurotransmitter. Activates α₁, α₂, β₁ adrenergic receptors. Locus coeruleus projects modulate CNS arousal. NET reuptake targeted by TCAs, SNRIs, cocaine, atomoxetine.

Entry Metadata

FieldValue
IDnorepinephrine
NameNorepinephrine
Statusdraft
Last reviewed2026-06-05
Atlas01-human
Scale03-molecular

Cross-Atlas Connections

modulatesBeta1 Adrenergic Receptor modulatesNervous System modulatesCardiovascular System modulated-byDopamine connects-toMajor Depressive Disorder connects-toPtsd connects-toAttention Deficit Hyperactivity Disorder connects-toGeneralized Anxiety Disorder connects-toPanic Disorder connects-toSocial Anxiety Disorder connects-toOpioid Use Disorder modulated-byOrexin connects-toBorderline Personality Disorder connects-toMu Opioid Receptor connects-toStimulant Use Disorder connects-toCrh connects-toAlcohol Use Disorder connects-toGambling Disorder connects-toFibromyalgia connects-toSubstance P connects-toNeuropathic Pain modulatesMelatonin

Sources