Atlas One · Host Biology · Scale 07 — System

Borderline Personality Disorder

Borderline personality disorder (2-5% prevalence; 75% female in clinical settings) involves emotional dysregulation, fear of abandonment, and unstable identity driven by amygdala hyperreactivity and PFC hypofunction; first-line: DBT; pharmacotherapy adjunctive only.

Also known as: borderline personality disorder, BPD, DBT, dialectical behavior therapy, emotional dysregulation, self-harm, non-suicidal self-injury, NSSI, McLean, Zanarini, invalidating environment

Scale 07 — SystemScale
draftStatus
2026-06-08Last Reviewed
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borderline-personality-disorder

Borderline Personality Disorder

Borderline personality disorder (2-5% prevalence; 75% female in clinical settings) involves emotional dysregulation, fear of abandonment, and unstable identity driven by amygdala hyperreactivity and PFC hypofunction; first-line: DBT; pharmacotherapy adjunctive only.

Entry Metadata

FieldValue
IDborderline-personality-disorder
NameBorderline Personality Disorder
Statusdraft
Last reviewed2026-06-08
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toSerotonin connects-toNorepinephrine connects-toCortisol targetsBrain connects-toOxytocin

Sources