Atlas One · Host Biology · Scale 07 — System

Epilepsy

Epilepsy (recurrent unprovoked seizures; 50M affected) comprises focal and generalized types; causes: structural, genetic (SCN1A-Dravet, KCNQ2, TSC1/2), autoimmune (anti-NMDAR), metabolic; valproate and levetiracetam are first-line; surgery and VNS for drug-refractory disease.

Also known as: epilepsy, seizure disorder, Dravet syndrome, temporal lobe epilepsy, MTLE, absence epilepsy, childhood absence, juvenile myoclonic epilepsy, JME, status epilepticus, GEFS+, West syndrome, Lennox-Gastaut syndrome, focal epilepsy, generalized epilepsy

Scale 07 — SystemScale
draftStatus
2026-06-08Last Reviewed
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epilepsy

Epilepsy

Epilepsy (recurrent unprovoked seizures; 50M affected) comprises focal and generalized types; causes: structural, genetic (SCN1A-Dravet, KCNQ2, TSC1/2), autoimmune (anti-NMDAR), metabolic; valproate and levetiracetam are first-line; surgery and VNS for drug-refractory disease.