Atlas One · Host Biology · Scale 02 — Atomic

Iodine

Iodine (I⁻, atomic number 53) — 15–20 mg total, ~75% in thyroid. Essential for T3/T4 synthesis via NIS uptake, TPO organification, and thyroglobulin coupling. Deficiency causes goitre, hypothyroidism, and cretinism — the leading preventable cause of intellectual disability.

Also known as: I, I-, iodide, iodine-127, organically-bound iodine

Scale 02 — AtomicScale
draftStatus
2026-06-05Last Reviewed
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iodine

Iodine

Iodine (I⁻, atomic number 53) — 15–20 mg total, ~75% in thyroid. Essential for T3/T4 synthesis via NIS uptake, TPO organification, and thyroglobulin coupling. Deficiency causes goitre, hypothyroidism, and cretinism — the leading preventable cause of intellectual disability.