Atlas One · Host Biology · Scale 03 — Molecular

Thyroid Hormones (T3/T4)

Iodinated tyrosine-derived hormones: T4 (prohormone, ~90% secreted) and active T3 (~10% secreted + 80% from peripheral deiodination). Nuclear TRα/TRβ receptors drive transcription, ↑BMR, ↑HR, linear growth, and fetal CNS development.

Also known as: thyroid hormones, T3, T4, thyroxine, triiodothyronine, levothyroxine, liothyronine, TSH, TRH, HPT axis, thyroid receptor, TR, TRα, TRβ, DIO1, DIO2, hypothyroidism, hyperthyroidism, Graves disease, Hashimoto thyroiditis

Scale 03 — MolecularScale
draftStatus
2026-06-05Last Reviewed
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thyroid-hormones

Thyroid Hormones (T3/T4)

Iodinated tyrosine-derived hormones: T4 (prohormone, ~90% secreted) and active T3 (~10% secreted + 80% from peripheral deiodination). Nuclear TRα/TRβ receptors drive transcription, ↑BMR, ↑HR, linear growth, and fetal CNS development.

Entry Metadata

FieldValue
IDthyroid-hormones
NameThyroid Hormones (T3/T4)
Statusdraft
Last reviewed2026-06-05
Atlas01-human
Scale03-molecular

Cross-Atlas Connections

modulatesCardiovascular System modulatesNervous System expressesThyroid modulatesLiver connects-toMajor Depressive Disorder connects-toOsteoporosis connects-toObesity connects-toBrain connects-toIodine connects-toSelenium

Sources