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selenium
Selenium
Selenium (Se, atomic number 34) — 13–20 mg total; selenocysteine in ~25 selenoproteins: GPx (antioxidant), thioredoxin reductase (redox homeostasis), and deiodinases (T4→T3). Deficiency causes Keshan cardiomyopathy, hypothyroidism, and impaired immune function.
Entry Metadata
| Field | Value |
|---|---|
| ID | selenium |
| Name | Selenium |
| Status | draft |
| Last reviewed | 2026-06-05 |
| Atlas | 01-human |
| Scale | 02-atomic |
Cross-Atlas Connections
Sources
- Berg JM, Tymoczko JL, Stryer L. Biochemistry. 9th ed. W.H. Freeman; 2019.
- Hall JE, Hall ME. Guyton and Hall Textbook of Medical Physiology. 14th ed. Elsevier; 2021.
- Labunskyy VM, Hatfield DL, Gladyshev VN. Selenoproteins: molecular pathways and physiological roles. Physiol Rev. 2014;94(3):739-77. · PubMed 24987004
- Forcina GC, Dixon SJ. GPX4 at the crossroads of lipid peroxidation and ferroptosis. Proteomics. 2019;19(18):e1800311. · PubMed 30924297