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mast-cell
Mast Cell
Tissue-resident innate immune cells with electron-dense metachromatic granules. IgE-FcεRI crosslinking triggers rapid degranulation releasing histamine, tryptase, leukotrienes, and PGD2. Central to type I hypersensitivity, allergic asthma, and host defence against parasites.
Entry Metadata
| Field | Value |
|---|---|
| ID | mast-cell |
| Name | Mast Cell |
| Status | draft |
| Last reviewed | 2026-06-05 |
| Atlas | 01-human |
| Scale | 04-cellular |