Atlas One · Host Biology · Scale 07 — System

Malaria

Malaria (Plasmodium falciparum primarily) kills ~600,000 annually; Anopheles-transmitted sporozoites → hepatocytes → RBC invasion → haemolysis + fever cycles; artemisinin-based combination therapy is first-line; G6PD and HbS variants confer partial protective advantage.

Also known as: malaria, Plasmodium falciparum, P. falciparum, P. vivax, falciparum malaria, cerebral malaria, severe malaria, uncomplicated malaria, parasitaemia

Scale 07 — SystemScale
draftStatus
2026-06-08Last Reviewed
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malaria

Malaria

Malaria (Plasmodium falciparum primarily) kills ~600,000 annually; Anopheles-transmitted sporozoites → hepatocytes → RBC invasion → haemolysis + fever cycles; artemisinin-based combination therapy is first-line; G6PD and HbS variants confer partial protective advantage.

Entry Metadata

FieldValue
IDmalaria
NameMalaria
Statusdraft
Last reviewed2026-06-08
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toG6Pd connects-toHemoglobin connects-toSickle Cell Disease connects-toCkd

Sources