Atlas One · Host Biology · Scale 03 — Molecular

G6PD

G6PD (G6PD; chrXq28) is the pentose phosphate pathway enzyme that generates NADPH for glutathione reduction; X-linked deficiency (400M carriers) → oxidant-induced haemolytic anaemia; G-6-PD A− (Africa) and B− (Mediterranean) are the most common variants; protects vs malaria.

Also known as: G6PD, glucose-6-phosphate dehydrogenase, G-6-PD, G6PD deficiency, G6PDd, favism, G6PD enzyme, hexose monophosphate shunt

Scale 03 — MolecularScale
draftStatus
2026-06-08Last Reviewed
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g6pd

G6PD

G6PD (G6PD; chrXq28) is the pentose phosphate pathway enzyme that generates NADPH for glutathione reduction; X-linked deficiency (400M carriers) → oxidant-induced haemolytic anaemia; G-6-PD A− (Africa) and B− (Mediterranean) are the most common variants; protects vs malaria.

Entry Metadata

FieldValue
IDg6pd
NameG6PD
Statusdraft
Last reviewed2026-06-08
Atlas01-human
Scale03-molecular

Cross-Atlas Connections

connects-toMalaria connects-toHemoglobin connects-toSickle Cell Disease connects-toErythrocyte connects-toThalassemia connects-toNeutrophil

Sources