Atlas One · Host Biology · Scale 03 — Molecular

Transferrin

Transferrin (TF; 79 kDa; SIDERO domain) is the plasma iron-transport protein; binds Fe³⁺ with Kd ~10⁻²⁰ M at pH 7.4; TFR1/CD71-mediated endocytosis delivers iron to erythroid precursors; TSAT and ferritin together diagnose iron deficiency anemia vs iron overload.

Also known as: transferrin, TF, serotransferrin, siderophilin, TSAT, transferrin saturation, iron-binding protein, TFR1, transferrin receptor

Scale 03 — MolecularScale
draftStatus
2026-06-08Last Reviewed
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transferrin

Transferrin

Transferrin (TF; 79 kDa; SIDERO domain) is the plasma iron-transport protein; binds Fe³⁺ with Kd ~10⁻²⁰ M at pH 7.4; TFR1/CD71-mediated endocytosis delivers iron to erythroid precursors; TSAT and ferritin together diagnose iron deficiency anemia vs iron overload.

Entry Metadata

FieldValue
IDtransferrin
NameTransferrin
Statusdraft
Last reviewed2026-06-08
Atlas01-human
Scale03-molecular

Cross-Atlas Connections

connects-toHemoglobin connects-toHepcidin connects-toThalassemia connects-toSickle Cell Disease

Sources