This is an auto-generated stub page built from atlas entry frontmatter. A richer
hand-crafted page is planned. See the
atlas source
for the full entry including detailed body sections.
b-cell
B Cell
B lymphocyte — antibody-producing cell of adaptive immunity. Surface IgM/IgD BCR binds antigen; with Tfh help undergoes class-switch recombination and affinity maturation in germinal centers; differentiates into plasma cells and memory B cells.
Entry Metadata
| Field | Value |
|---|---|
| ID | b-cell |
| Name | B Cell |
| Status | draft |
| Last reviewed | 2026-06-04 |
| Atlas | 01-human |
| Scale | 04-cellular |
Cross-Atlas Connections
part-ofImmune System
modulated-byT Helper Cell
modulatesPlasma Cell
modulated-byNatural Killer Cell
modulated-byIntestinal Epithelium
part-ofBone Marrow
part-ofSpleen
modulated-byT Cytotoxic Cell
modulated-byRegulatory T Cell
infected-byEpstein Barr Virus
infected-byNorovirus
target-ofNorovirus Vp1
connects-toMyasthenia Gravis
infected-byHerpesvirus
Sources
- Nutt SL, Hodgkin PD, Tarlinton DM, Corcoran LM. The generation of antibody-secreting plasma cells. Nat Rev Immunol. 2015;15(3):160-71. · PubMed 25698678
- Victora GD, Nussenzweig MC. Germinal centers. Annu Rev Immunol. 2012;30:429-57. · PubMed 22224772
- Kurosaki T, Shinohara H, Baba Y. B cell signaling and fate decision. Annu Rev Immunol. 2010;28:21-55. · PubMed 20192804
- Abbas AK, Lichtman AH, Pillai S. Cellular and Molecular Immunology. 9th ed. Elsevier; 2018.