This is an auto-generated stub page built from atlas entry frontmatter. A richer
hand-crafted page is planned. See the
atlas source
for the full entry including detailed body sections.
plasma-cell
Plasma Cell
Terminal effector of B cell differentiation — large oval cell with eccentric nucleus, clock-face chromatin, and massive rough ER secreting 1,000–10,000 antibodies/sec. Long-lived plasma cells in bone marrow are the cellular basis of durable humoral immunity.
Entry Metadata
| Field | Value |
|---|---|
| ID | plasma-cell |
| Name | Plasma Cell |
| Status | draft |
| Last reviewed | 2026-06-04 |
| Atlas | 01-human |
| Scale | 04-cellular |
Cross-Atlas Connections
Sources
- Slifka MK, Antia R, Whitmire JK, Ahmed R. Humoral immunity due to long-lived plasma cells. Immunity. 1998;8(3):363-72. · PubMed 9529153
- Nutt SL, Hodgkin PD, Tarlinton DM, Corcoran LM. The generation of antibody-secreting plasma cells. Nat Rev Immunol. 2015;15(3):160-71. · PubMed 25698678
- Amanna IJ, Slifka MK. Mechanisms that determine plasma cell lifespan and the duration of humoral immunity. Immunol Rev. 2010;236(1):125-38. · PubMed 20636813
- Turner JS, et al. SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses. Nature. 2021;596(7870):109-113. · PubMed 34182569