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t-cytotoxic-cell
Cytotoxic T Cell
CD8+ αβ T lymphocyte; 20–35% of circulating T cells. Recognises MHC-I:peptide on all nucleated cells; kills virus-infected and tumour targets via perforin/granzyme B and Fas/FasL. Forms long-lived memory subsets (T_CM, T_EM, T_RM) and exhausts under chronic antigen exposure.
Entry Metadata
| Field | Value |
|---|---|
| ID | t-cytotoxic-cell |
| Name | Cytotoxic T Cell |
| Status | draft |
| Last reviewed | 2026-06-05 |
| Atlas | 01-human |
| Scale | 04-cellular |