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norovirus
Norovirus
Norovirus (Caliciviridae; GII.4 pandemic strains; ~7.7 kb +ssRNA; non-enveloped) causes acute viral gastroenteritis; infective dose ~18 particles; VP1-HBGA binding drives entry; 685 million cases/year; 200K deaths/year; no approved vaccine; nitazoxanide investigational.
Entry Metadata
| Field | Value |
|---|---|
| ID | norovirus |
| Name | Norovirus |
| Status | draft |
| Last reviewed | 2026-06-08 |
| Atlas | 01-human |
| Scale | 07-system |
Cross-Atlas Connections
Sources
- Ahmed SM, Hall AJ, Robinson AE, et al. Global prevalence of norovirus in cases of gastroenteritis: a systematic review and meta-analysis. Lancet Infect Dis. 2014;14(8):725-730. · PubMed 24981041
- Robilotti E, Deresiewicz RL, Bhatt S. Norovirus. Clin Microbiol Rev. 2015;28(1):134-164. · PubMed 25567225
- Jones MK, Watanabe M, Zhu S, et al. Enteric bacteria promote human and mouse norovirus infection of B cells. Science. 2014;346(6210):755-759. · PubMed 25237103
- Lindesmith L, Moe C, Marionneau S, et al. Human susceptibility and resistance to Norwalk virus infection. Nat Med. 2003;9(5):548-553. · PubMed 12692541