Atlas One · Host Biology · Scale 03 — Molecular

Secretory IgA

Dimeric IgA + J chain + secretory component (SC); dominant mucosal antibody in gut, saliva, colostrum. Transcytosed via pIgR. SC confers protease resistance. Functions: immune exclusion, viral neutralization, pathogen agglutination.

Also known as: SIgA, secretory IgA, sIgA, dimeric IgA, mucosal IgA

Scale 03 — MolecularScale
draftStatus
2026-06-06Last Reviewed
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secretory-iga

Secretory IgA

Dimeric IgA + J chain + secretory component (SC); dominant mucosal antibody in gut, saliva, colostrum. Transcytosed via pIgR. SC confers protease resistance. Functions: immune exclusion, viral neutralization, pathogen agglutination.

Entry Metadata

FieldValue
IDsecretory-iga
NameSecretory IgA
Statusdraft
Last reviewed2026-06-06
Atlas01-human
Scale03-molecular

Cross-Atlas Connections

expressed-byPlasma Cell connects-toImmunoglobulin G connects-toGut Microbiome connects-toImmune System connects-toIga Nephropathy connects-toGerminal Center

Sources