Atlas One · Host Biology · Scale 03 — Molecular

Ghrelin

Ghrelin (GHRL, chr3p25.3) is the only circulating orexigenic hormone; n-octanoyl Ser3 acylation by GOAT is required for GHSR1a binding; ghrelin → GH release and appetite stimulation; Prader-Willi syndrome has pathologically high ghrelin; anamorelin treats cancer cachexia.

Also known as: ghrelin, GHRL, growth hormone secretagogue, motilin-related peptide, des-acyl ghrelin, appetite hormone

Scale 03 — MolecularScale
draftStatus
2026-06-07Last Reviewed
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ghrelin

Ghrelin

Ghrelin (GHRL, chr3p25.3) is the only circulating orexigenic hormone; n-octanoyl Ser3 acylation by GOAT is required for GHSR1a binding; ghrelin → GH release and appetite stimulation; Prader-Willi syndrome has pathologically high ghrelin; anamorelin treats cancer cachexia.

Entry Metadata

FieldValue
IDghrelin
NameGhrelin
Statusdraft
Last reviewed2026-06-07
Atlas01-human
Scale03-molecular

Cross-Atlas Connections

connects-toDigestive System connects-toType 2 Diabetes connects-toIgf 1 connects-toObesity connects-toBulimia Nervosa connects-toBinge Eating Disorder

Sources