Atlas One · Host Biology · Scale 03 — Molecular

Resistin

Resistin is a monocyte-secreted cytokine (RETN) that activates NF-κB → insulin resistance, endothelial dysfunction, and hepatic VLDL secretion; elevated in NASH, T2D, and rheumatoid arthritis; inhibits adiponectin signaling and promotes pro-inflammatory macrophage activation.

Also known as: resistin, RETN, ADSF, FIZZ3, resistin-like molecule, adipokine, adipocytokine, hyperresistinemia, CAP1

Scale 03 — MolecularScale
draftStatus
2026-06-07Last Reviewed
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resistin

Resistin

Resistin is a monocyte-secreted cytokine (RETN) that activates NF-κB → insulin resistance, endothelial dysfunction, and hepatic VLDL secretion; elevated in NASH, T2D, and rheumatoid arthritis; inhibits adiponectin signaling and promotes pro-inflammatory macrophage activation.