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adrenomedullin
Adrenomedullin
Adrenomedullin (ADM) is a 52-aa vasodilatory peptide from adrenal medulla and endothelium; CLR/RAMP2 → cAMP → NO → vasodilation and vascular barrier protection; mid-regional pro-ADM (MR-proADM) is a sepsis severity biomarker and guides antibiotic duration.
Entry Metadata
| Field | Value |
|---|---|
| ID | adrenomedullin |
| Name | Adrenomedullin |
| Status | draft |
| Last reviewed | 2026-06-07 |
| Atlas | 01-human |
| Scale | 03-molecular |
Cross-Atlas Connections
Sources
- Kitamura K, Kangawa K, Kawamoto M, et al. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun. 1993;192(2):553-560. · PubMed 8387282
- Schuetz P, Wolbers M, Christ-Crain M, et al. Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections. Crit Care. 2010;14(3):R106. · PubMed 20529248