Atlas One · Host Biology · Scale 07 — System

Chronic Kidney Disease

Progressive irreversible loss of kidney function (GFR <60 mL/min for >3 months) from diabetes, hypertension, or glomerulonephritis. Staged G1-G5 by GFR; complications include anemia, hyperparathyroidism, and uremia. End-stage managed by dialysis or transplantation.

Also known as: CKD, chronic renal failure, chronic renal insufficiency, end-stage kidney disease, ESKD

Scale 07 — SystemScale
draftStatus
2026-06-06Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
ckd

Chronic Kidney Disease

Progressive irreversible loss of kidney function (GFR <60 mL/min for >3 months) from diabetes, hypertension, or glomerulonephritis. Staged G1-G5 by GFR; complications include anemia, hyperparathyroidism, and uremia. End-stage managed by dialysis or transplantation.

Entry Metadata

FieldValue
IDckd
NameChronic Kidney Disease
Statusdraft
Last reviewed2026-06-06
Atlas01-human
Scale07-system

Cross-Atlas Connections

targetsKidney part-ofRenal System modulatesErythropoietin connects-toHypertension connects-toSglt2 connects-toFgf23 connects-toOsteopontin connects-toIga Nephropathy connects-toHepcidin connects-toAnemia Of Chronic Disease connects-toAhus connects-toSickle Cell Disease connects-toMalaria connects-toSclerostin connects-toPrurigo Nodularis

Sources