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troponin-complex
Troponin complex
Heterotrimeric calcium switch on the thin filament — TnC binds Ca²⁺, TnI inhibits actomyosin in its absence, TnT anchors the complex to tropomyosin. The molecular gate of every heartbeat.
Entry Metadata
| Field | Value |
|---|---|
| ID | troponin-complex |
| Name | Troponin complex |
| Status | draft |
| Last reviewed | 2026-06-03 |
| Atlas | 01-human |
| Scale | 03-molecular |
| Uniprot | P63316,P19429,P45379 |
| Gene Symbol | TNNC1,TNNI3,TNNT2 |
Cross-Atlas Connections
Sources
- OpenStax. Anatomy & Physiology 2e, Ch. 19.2: Cardiac Muscle and Electrical Activity.
- Bers DM. Cardiac excitation-contraction coupling. Nature. 2002;415(6868):198-205. · PubMed 11805843
- UniProt P63316 — Troponin C, slow skeletal and cardiac muscles (TNNC1, human).
- UniProt P19429 — Troponin I, cardiac muscle (TNNI3, human).
- UniProt P45379 — Troponin T, cardiac muscle (TNNT2, human).
- Thygesen K, Alpert JS, Jaffe AS, et al. Fourth Universal Definition of Myocardial Infarction (2018). J Am Coll Cardiol. 2018;72(18):2231-64. · PubMed 30153967