This is an auto-generated stub page built from atlas entry frontmatter. A richer
hand-crafted page is planned. See the
atlas source
for the full entry including detailed body sections.
atherosclerosis
Atherosclerosis
Chronic arterial intimal disease driven by LDL oxidation, macrophage foam cell formation, and smooth muscle migration; vulnerable plaque rupture causes MI and stroke. Statins, PCSK9 inhibitors, and anti-inflammatory therapies (colchicine) are evidence-based interventions.
Entry Metadata
| Field | Value |
|---|---|
| ID | atherosclerosis |
| Name | Atherosclerosis |
| Status | draft |
| Last reviewed | 2026-06-06 |
| Atlas | 01-human |
| Scale | 07-system |
Cross-Atlas Connections
Sources
- Ross R. Atherosclerosis — an inflammatory disease. N Engl J Med. 1999;340(2):115-126. · PubMed 9887164
- Ridker PM, Everett BM, Thuren T, et al. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease. N Engl J Med. 2017;377(12):1119-1131. · PubMed 28845751
- Sabatine MS, Giugliano RP, Keech AC, et al. Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease. N Engl J Med. 2017;376(18):1713-1722. · PubMed 28304224