Atlas One · Host Biology · Scale 03 — Molecular

Fibrinogen

340 kDa plasma glycoprotein (hexamer [AαBβγ]₂); synthesised by hepatocytes at 2–4 g/L. Thrombin cleaves fibrinopeptides A and B → fibrin → crosslinked clot (FXIIIa). Positive acute-phase reactant; elevated fibrinogen is an independent CVD risk factor.

Also known as: factor I, fibrin, Fg, fibrin monomer, fibrin clot

Scale 03 — MolecularScale
draftStatus
2026-06-05Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
fibrinogen

Fibrinogen

340 kDa plasma glycoprotein (hexamer [AαBβγ]₂); synthesised by hepatocytes at 2–4 g/L. Thrombin cleaves fibrinopeptides A and B → fibrin → crosslinked clot (FXIIIa). Positive acute-phase reactant; elevated fibrinogen is an independent CVD risk factor.