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wound-healing
Wound Healing
Wound healing: hemostasis → inflammation → proliferation (granulation + re-epithelialization) → remodeling. PDGF, TGF-β, VEGF, FN, and EGF orchestrate each phase. Chronic wounds arise from impaired M1→M2 switch; diabetic ulcers are the leading cause of non-traumatic amputation.
Entry Metadata
| Field | Value |
|---|---|
| ID | wound-healing |
| Name | Wound Healing |
| Status | draft |
| Last reviewed | 2026-06-07 |
| Atlas | 01-human |
| Scale | 07-system |
Cross-Atlas Connections
connects-toFibronectin
connects-toTgf Beta
connects-toVegf
connects-toDiabetic Retinopathy
connects-toMacrophage
connects-toFibroblast
connects-toSkin
connects-toPlatelet
connects-toCollagen
connects-toSystemic Sclerosis
connects-toType 2 Diabetes
connects-toEndothelial Cell
connects-toIntegumentary System
connects-toNeutrophil
connects-toPdgf
connects-toObesity
connects-toFibrosis
connects-toOxygen
connects-toT Helper Cell
connects-toPeripheral Nerve
connects-toSmooth Muscle Cell
connects-toMast Cell
connects-toThrombin
connects-toHif 1Alpha
connects-toZinc
connects-toCopper
connects-toCortisol
connects-toRegulatory T Cell
connects-toIl 6
connects-toLarge Intestine
connects-toDendritic Cell
connects-toPhoton
connects-toLiver
connects-toIron
connects-toElectron
connects-toCalcium
connects-toVitamin D
connects-toAlbumin
connects-toErythrocyte
connects-toNitric Oxide
connects-toAngiopoietin
connects-toStaphylococcus Aureus
connects-toSepsis
connects-toEstrogen
connects-toAdipocyte
connects-toCkd
connects-toTnf Alpha
connects-toHistamine
connects-toBradykinin
connects-toStat3
connects-toNf Kb
connects-toVenous Thromboembolism
connects-toCandida Albicans
connects-toAtherosclerosis
connects-toAnemia Of Chronic Disease
connects-toRheumatoid Arthritis
connects-toOsteoporosis
connects-toMajor Depressive Disorder
connects-toImmune System
connects-toLymphatic System
connects-toStreptococcus Pyogenes
connects-toNervous System
connects-toEndocrine System
connects-toMusculoskeletal System
connects-toCardiovascular System
connects-toRespiratory System
connects-toReproductive System
connects-toDigestive System
connects-toRenal System
connects-toZinc Dietary
connects-toCorticosteroids
connects-toClostridium Tetani
connects-toCancer Chemotherapy
connects-toCortical Bone
connects-toType 1 Diabetes
connects-toMyocardium
connects-toInflammatory Bowel Disease
connects-toPancreatic Cancer
connects-toAlveolus
connects-toArterial Wall
connects-toHepatic Lobule
connects-toFgfr
connects-toEgfr
connects-toIl 1B
connects-toIgf 1
connects-toCcl2
connects-toIl 10
connects-toWnt Beta Catenin
connects-toProstaglandins
connects-toPeriostin
connects-toSubstance P
connects-toIl 4
connects-toRage
connects-toS100A8 A9
connects-toMet
connects-toConnexin43
connects-toCxcl12
connects-toErk1 2
connects-toAkt
connects-toSmad4
connects-toTlr4
connects-toMtor
connects-toNfe2L2
connects-toGalectin 3
connects-toStat1
connects-toCgas Sting
connects-toFoxo
connects-toJak1 2
connects-toPik3Ca
connects-toGsk 3B
connects-toSrc Kinase
connects-toCdk4 6
connects-toAmpk
connects-toAutophagy
connects-toNotch
connects-toCcr5
connects-toDnmt3A
connects-toFibrinogen
connects-toIl 33
connects-toIl 17A
connects-toArid1A
connects-toInsulin
connects-toSerotonin
connects-toNlrp3 Inflammasome
connects-toOmega 3 Fatty Acids
connects-toLeptin
connects-toIl 13
connects-toXanthine Oxidase
connects-toCgrp
connects-toAdenosine
connects-toNeutrophil
connects-toType 2 Diabetes
connects-toOxygen
connects-toAdiponectin
connects-toResistin
connects-toHepcidin
connects-toMacrophage
connects-toPlatelet
connects-toCopper
connects-toT Cytotoxic Cell
connects-toIfn Gamma
connects-toIl 5
connects-toIl 12
connects-toIl 23
connects-toType I Interferon
connects-toIge
connects-toTslp
connects-toIl 31
connects-toComplement C3
connects-toC5Ar1
connects-toFactor H
connects-toC1 Esterase Inhibitor
connects-toErythropoietin
connects-toComplement C5
connects-toMelatonin
connects-toProlactin
connects-toOxytocin
connects-toTestosterone
connects-toVasopressin
connects-toSelenium
connects-toIodine
connects-toSodium
connects-toMagnesium
connects-toPotassium
connects-toPhosphorus
connects-toChloride
connects-toSulfur
connects-toNitrogen
connects-toCarbon
connects-toPd 1
connects-toGlp 1
connects-toAngiotensin Ii
connects-toHydrogen
connects-toRankl
connects-toIl 2
connects-toActivin A
connects-toCalcitonin
connects-toFgf23
connects-toInsulin Receptor
connects-toAldosterone
connects-toAndrogen Receptor
connects-toAdrenomedullin
connects-toEndothelin 1
connects-toOsteopontin
connects-toNorepinephrine
connects-toBdnf
connects-toEpinephrine
connects-toRenin
connects-toMyostatin
connects-toGalectin 3
connects-toGhrelin
connects-toGlucagon
connects-toAcetylcholine
Sources
- Singer AJ, Clark RA. Cutaneous wound healing. N Engl J Med. 1999;341(10):738-746. · PubMed 10471461
- Gurtner GC, Werner S, Barrandon Y, Longaker MT. Wound repair and regeneration. Nature. 2008;453(7193):314-321. · PubMed 18480812
- Eming SA, Martin P, Tomic-Canic M. Wound repair and regeneration: mechanisms, signaling, and translation. Sci Transl Med. 2014;6(265):265sr6. · PubMed 25473038