Atlas One · Host Biology · Scale 07 — System

Wound Healing

Wound healing: hemostasis → inflammation → proliferation (granulation + re-epithelialization) → remodeling. PDGF, TGF-β, VEGF, FN, and EGF orchestrate each phase. Chronic wounds arise from impaired M1→M2 switch; diabetic ulcers are the leading cause of non-traumatic amputation.

Also known as: wound repair, cutaneous wound healing, tissue repair, skin healing, chronic wound, diabetic wound

Scale 07 — SystemScale
draftStatus
2026-06-07Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
wound-healing

Wound Healing

Wound healing: hemostasis → inflammation → proliferation (granulation + re-epithelialization) → remodeling. PDGF, TGF-β, VEGF, FN, and EGF orchestrate each phase. Chronic wounds arise from impaired M1→M2 switch; diabetic ulcers are the leading cause of non-traumatic amputation.

Entry Metadata

FieldValue
IDwound-healing
NameWound Healing
Statusdraft
Last reviewed2026-06-07
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toFibronectin connects-toTgf Beta connects-toVegf connects-toDiabetic Retinopathy connects-toMacrophage connects-toFibroblast connects-toSkin connects-toPlatelet connects-toCollagen connects-toSystemic Sclerosis connects-toType 2 Diabetes connects-toEndothelial Cell connects-toIntegumentary System connects-toNeutrophil connects-toPdgf connects-toObesity connects-toFibrosis connects-toOxygen connects-toT Helper Cell connects-toPeripheral Nerve connects-toSmooth Muscle Cell connects-toMast Cell connects-toThrombin connects-toHif 1Alpha connects-toZinc connects-toCopper connects-toCortisol connects-toRegulatory T Cell connects-toIl 6 connects-toLarge Intestine connects-toDendritic Cell connects-toPhoton connects-toLiver connects-toIron connects-toElectron connects-toCalcium connects-toVitamin D connects-toAlbumin connects-toErythrocyte connects-toNitric Oxide connects-toAngiopoietin connects-toStaphylococcus Aureus connects-toSepsis connects-toEstrogen connects-toAdipocyte connects-toCkd connects-toTnf Alpha connects-toHistamine connects-toBradykinin connects-toStat3 connects-toNf Kb connects-toVenous Thromboembolism connects-toCandida Albicans connects-toAtherosclerosis connects-toAnemia Of Chronic Disease connects-toRheumatoid Arthritis connects-toOsteoporosis connects-toMajor Depressive Disorder connects-toImmune System connects-toLymphatic System connects-toStreptococcus Pyogenes connects-toNervous System connects-toEndocrine System connects-toMusculoskeletal System connects-toCardiovascular System connects-toRespiratory System connects-toReproductive System connects-toDigestive System connects-toRenal System connects-toZinc Dietary connects-toCorticosteroids connects-toClostridium Tetani connects-toCancer Chemotherapy connects-toCortical Bone connects-toType 1 Diabetes connects-toMyocardium connects-toInflammatory Bowel Disease connects-toPancreatic Cancer connects-toAlveolus connects-toArterial Wall connects-toHepatic Lobule connects-toFgfr connects-toEgfr connects-toIl 1B connects-toIgf 1 connects-toCcl2 connects-toIl 10 connects-toWnt Beta Catenin connects-toProstaglandins connects-toPeriostin connects-toSubstance P connects-toIl 4 connects-toRage connects-toS100A8 A9 connects-toMet connects-toConnexin43 connects-toCxcl12 connects-toErk1 2 connects-toAkt connects-toSmad4 connects-toTlr4 connects-toMtor connects-toNfe2L2 connects-toGalectin 3 connects-toStat1 connects-toCgas Sting connects-toFoxo connects-toJak1 2 connects-toPik3Ca connects-toGsk 3B connects-toSrc Kinase connects-toCdk4 6 connects-toAmpk connects-toAutophagy connects-toNotch connects-toCcr5 connects-toDnmt3A connects-toFibrinogen connects-toIl 33 connects-toIl 17A connects-toArid1A connects-toInsulin connects-toSerotonin connects-toNlrp3 Inflammasome connects-toOmega 3 Fatty Acids connects-toLeptin connects-toIl 13 connects-toXanthine Oxidase connects-toCgrp connects-toAdenosine connects-toNeutrophil connects-toType 2 Diabetes connects-toOxygen connects-toAdiponectin connects-toResistin connects-toHepcidin connects-toMacrophage connects-toPlatelet connects-toCopper connects-toT Cytotoxic Cell connects-toIfn Gamma connects-toIl 5 connects-toIl 12 connects-toIl 23 connects-toType I Interferon connects-toIge connects-toTslp connects-toIl 31 connects-toComplement C3 connects-toC5Ar1 connects-toFactor H connects-toC1 Esterase Inhibitor connects-toErythropoietin connects-toComplement C5 connects-toMelatonin connects-toProlactin connects-toOxytocin connects-toTestosterone connects-toVasopressin connects-toSelenium connects-toIodine connects-toSodium connects-toMagnesium connects-toPotassium connects-toPhosphorus connects-toChloride connects-toSulfur connects-toNitrogen connects-toCarbon connects-toPd 1 connects-toGlp 1 connects-toAngiotensin Ii connects-toHydrogen connects-toRankl connects-toIl 2 connects-toActivin A connects-toCalcitonin connects-toFgf23 connects-toInsulin Receptor connects-toAldosterone connects-toAndrogen Receptor connects-toAdrenomedullin connects-toEndothelin 1 connects-toOsteopontin connects-toNorepinephrine connects-toBdnf connects-toEpinephrine connects-toRenin connects-toMyostatin connects-toGalectin 3 connects-toGhrelin connects-toGlucagon connects-toAcetylcholine