Atlas One · Host Biology · Scale 07 — System

Diabetic Retinopathy

Diabetic retinopathy (DR) is the leading cause of blindness in working-age adults; hyperglycemia → pericyte loss → microaneurysms → neovascularization (PDR) → vitreous hemorrhage. VEGF + Ang-2 drive macular edema; anti-VEGF and faricimab are the treatment standard.

Also known as: DR, diabetic eye disease, non-proliferative DR, NPDR, proliferative DR, PDR, diabetic macular edema, DME, center-involving DME

Scale 07 — SystemScale
draftStatus
2026-06-07Last Reviewed
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diabetic-retinopathy

Diabetic Retinopathy

Diabetic retinopathy (DR) is the leading cause of blindness in working-age adults; hyperglycemia → pericyte loss → microaneurysms → neovascularization (PDR) → vitreous hemorrhage. VEGF + Ang-2 drive macular edema; anti-VEGF and faricimab are the treatment standard.