Atlas One · Host Biology · Scale 03 — Molecular

GLP-1

GLP-1 is an incretin produced by intestinal L-cells; binds GLP-1R → cAMP → glucose-dependent insulin secretion and β-cell proliferation; GLP-1R agonists (semaglutide, liraglutide) are first-line therapy for type 2 diabetes and obesity with proven cardiovascular benefit.

Also known as: GLP-1, glucagon-like peptide 1, GLP1, incretin, GLP-1 receptor agonist, semaglutide target, liraglutide target, GLP-1R agonist, tirzepatide GLP1, Ozempic mechanism

Scale 03 — MolecularScale
draftStatus
2026-06-07Last Reviewed
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glp-1

GLP-1

GLP-1 is an incretin produced by intestinal L-cells; binds GLP-1R → cAMP → glucose-dependent insulin secretion and β-cell proliferation; GLP-1R agonists (semaglutide, liraglutide) are first-line therapy for type 2 diabetes and obesity with proven cardiovascular benefit.

Entry Metadata

FieldValue
IDglp-1
NameGLP-1
Statusdraft
Last reviewed2026-06-07
Atlas01-human
Scale03-molecular

Cross-Atlas Connections

connects-toType 2 Diabetes connects-toNash connects-toGlucagon connects-toInsulin connects-toObesity connects-toCardiovascular System connects-toBrain connects-toAlzheimers Disease

Sources