Glomerulus

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glomerulus

Tuft of fenestrated capillaries (~8–10 loops) in Bowman's capsule — the nephron's primary filtration unit. Three-layer barrier filters ~180 L/day of plasma at GFR ~125 mL/min. ~1 million glomeruli per adult kidney.

Entry Metadata

Field	Value
ID	glomerulus
Name	Glomerulus
Status	draft
Last reviewed	2026-06-04
Atlas	01-human
Scale	05-tissue

Cross-Atlas Connections

containsPodocyte part-ofKidney part-ofRenal System connects-toCardiovascular System damaged-bySars Cov 2 modulated-byCardiovascular System composed-ofCollagen modulated-byComplement C3 modulated-byAlbumin connects-toFactor H

Sources

Haraldsson B, Nystrom J, Deen WM. Properties of the glomerular barrier and mechanisms of proteinuria. Physiol Rev. 2008;88(2):451-87. · PubMed 18391170
Hall JE. Guyton and Hall Textbook of Medical Physiology. 14th ed. Elsevier; 2021. Ch. 26-27.
Quaggin SE, Kreidberg JA. Development of the renal glomerulus: good neighbors and good fences. Development. 2008;135(4):609-20. · PubMed 18223199
Kriz W, Hackenthal E, Nobiling R, Sakai T, Elger M, Hähnel B. A role for podocytes to counteract capillary wall distension. Kidney Int. 1994;45(2):369-76. · PubMed 8164423
Tryggvason K, Patrakka J, Wartiovaara J. Hereditary proteinuria syndromes and mechanisms of proteinuria. N Engl J Med. 2006;354(13):1387-401. · PubMed 16571882