Atlas One · Host Biology · Scale 07 — System

SARS-CoV-2

SARS-CoV-2 (betacoronavirus; sarbecovirus; ~29.9 kb +ssRNA) causes COVID-19 via ACE2/Spike entry; NSP1-16 replicase includes NSP12 RdRp (remdesivir target) and Mpro NSP5 (nirmatrelvir target); multiple IFN evasion proteins; Omicron R₀ >10; mRNA vaccines >90% vs severe disease.

Also known as: SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, 2019-nCoV, COVID-19 virus, betacoronavirus, sarbecovirus, coronavirus

Scale 07 — SystemScale
draftStatus
2026-06-08Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
sars-cov-2

SARS-CoV-2

SARS-CoV-2 (betacoronavirus; sarbecovirus; ~29.9 kb +ssRNA) causes COVID-19 via ACE2/Spike entry; NSP1-16 replicase includes NSP12 RdRp (remdesivir target) and Mpro NSP5 (nirmatrelvir target); multiple IFN evasion proteins; Omicron R₀ >10; mRNA vaccines >90% vs severe disease.

Entry Metadata

FieldValue
IDsars-cov-2
NameSARS-CoV-2
Statusdraft
Last reviewed2026-06-08
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toSars Cov 2 Spike connects-toAce2 connects-toCovid 19 Disease connects-toType I Interferon connects-toMavs connects-toNf Kb connects-toCgas Sting connects-toSelenium connects-toIodine connects-toSodium connects-toFibronectin connects-toNotch connects-toIgf 1 connects-toActivin A connects-toTgf Beta connects-toCgrp connects-toCalcitonin connects-toSubstance P connects-toInsulin Receptor connects-toAldosterone connects-toAndrogen Receptor connects-toNorepinephrine connects-toAdrenomedullin connects-toBdnf connects-toOsteopontin connects-toFgfr connects-toEpinephrine connects-toRenin connects-toMyostatin connects-toGalectin 3 connects-toAngiopoietin connects-toResistin connects-toCortisol connects-toGhrelin connects-toGlucagon connects-toLeptin connects-toProlactin connects-toEstrogen connects-toAcetylcholine connects-toAdenosine connects-toApoe connects-toTestosterone connects-toIl 2 connects-toIl 10 connects-toIl 12 connects-toIl 17A connects-toIl 13 connects-toIl 1B connects-toIl 4 connects-toIl 5 connects-toIl 6 connects-toIl 23 connects-toIl 31 connects-toIl 33 connects-toIl 36 connects-toTnf Alpha connects-toIfn Gamma connects-toStat1 connects-toStat3 connects-toJak2 connects-toAkt connects-toMtor connects-toAmpk connects-toHif 1Alpha connects-toCcl2 connects-toCxcl12 connects-toEgfr connects-toErk1 2 connects-toFoxo connects-toFoxo1 connects-toJak1 2 connects-toMhc Class Ii connects-toPdgf connects-toVegf connects-toComplement C3 connects-toComplement C5 connects-toWnt Beta Catenin connects-toCgas Sting connects-toAutophagy connects-toBcl 2 connects-toAce2 connects-toBtk connects-toCaspase 3 connects-toCd20 connects-toCdk4 6 connects-toCyclin D1 connects-toAdiponectin connects-toAngiotensin Ii connects-toAlbumin connects-toActh connects-toAbl1 connects-toAdamts13 connects-toAlk connects-toAntibody connects-toAntithrombin connects-toApc connects-toApp connects-toAquaporin 4 connects-toArid1A connects-toAtm connects-toAtp connects-toAtrx connects-toAxl Receptor connects-toBaff connects-toBap1 connects-toBradykinin connects-toBraf connects-toBrca1 connects-toBrca2 connects-toCalcineurin connects-toCalr connects-toBlm connects-toC5Ar1 connects-toCcr5 connects-toCd30 connects-toCdkn1A connects-toCdkn2A connects-toBnp connects-toCdkn1B connects-toCftr connects-toCholesterol

Sources