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kidney
Kidney
Paired retroperitoneal organs (~150 g each) housing ~1 million nephrons. Core functions: plasma filtration (GFR ~125 mL/min), tubular reabsorption, acid-base balance, and endocrine roles (EPO, renin, calcitriol). Central to blood pressure regulation via RAAS.
Entry Metadata
| Field | Value |
|---|---|
| ID | kidney |
| Name | Kidney |
| Status | draft |
| Last reviewed | 2026-06-04 |
| Atlas | 01-human |
| Scale | 06-organ |
| Uberon | UBERON:0002113 |
| Fma | FMA:7203 |
Cross-Atlas Connections
containsGlomerulus
containsPodocyte
part-ofRenal System
connects-toCardiovascular System
damaged-bySars Cov 2
treated-byAce Inhibitors
treated-byLoop Diuretics
modulated-byVasopressin
modulated-byAngiotensin Ii
modulated-byAlbumin
expressed-byErythropoietin
modulated-byChloride
modulated-byVitamin D
modulated-byLicorice Root
damaged-byVancomycin
connects-toHydrogen
connects-toSodium
modulated-byBeta Blockers
Sources
- Hall JE. Guyton and Hall Textbook of Medical Physiology. 14th ed. Elsevier; 2021. Ch. 26-32.
- Levey AS, Coresh J, Balk E, et al. National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann Intern Med. 2003;139(2):137-47. · PubMed 12859163
- Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int Suppl. 2013;3(1):1-150.
- Kidney Disease: Improving Global Outcomes (KDIGO) AKI Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Int Suppl. 2012;2(1):1-138.
- Vanholder R, Annemans L, Brown E, et al. Reducing the costs of chronic kidney disease while delivering quality health care: a call to action. Nat Rev Nephrol. 2017;13(7):393-409. · PubMed 28479604