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neuropathic-pain
Neuropathic Pain
Neuropathic pain arises from peripheral nerve injury or CNS lesion; ectopic discharge, spinal wind-up (NMDA/SP), and central sensitization maintain pain beyond healing. FDA-approved treatments: duloxetine, pregabalin, gabapentin, and topical agents.
Entry Metadata
| Field | Value |
|---|---|
| ID | neuropathic-pain |
| Name | Neuropathic Pain |
| Status | draft |
| Last reviewed | 2026-06-08 |
| Atlas | 01-human |
| Scale | 07-system |
Cross-Atlas Connections
Sources
- Jensen TS, Baron R, Haanpää M, et al. A new definition of neuropathic pain. Pain. 2011;152(10):2204-2205. · PubMed 21764514
- Dworkin RH, O'Connor AB, Audette J, et al. Recommendations for the pharmacological management of neuropathic pain: an overview and literature update. Mayo Clin Proc. 2010;85(3 Suppl):S3-14. · PubMed 20194146
- Scholz J, Woolf CJ. Can we conquer pain? Nat Neurosci. 2002;5(Suppl):1062-1067. · PubMed 12403987