Atlas One · Host Biology · Scale 07 — System

NMOSD

NMOSD: AQP4-IgG+ (85%) or MOG-IgG+ attacks on optic nerves, spinal cord, and brainstem (area postrema); relapsing; high morbidity. Eculizumab (PREVENT; FDA Jun 2019), inebilizumab (N-MOmentum; FDA Jun 2020), satralizumab (SAkuraStar; FDA Aug 2020) approved.

Also known as: NMOSD, neuromyelitis optica spectrum disorder, NMO, Devic's disease, neuromyelitis optica, AQP4-IgG neuropathy, anti-AQP4 disease, MOG-IgG disease

Scale 07 — SystemScale
draftStatus
2026-06-07Last Reviewed
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nmo

NMOSD

NMOSD: AQP4-IgG+ (85%) or MOG-IgG+ attacks on optic nerves, spinal cord, and brainstem (area postrema); relapsing; high morbidity. Eculizumab (PREVENT; FDA Jun 2019), inebilizumab (N-MOmentum; FDA Jun 2020), satralizumab (SAkuraStar; FDA Aug 2020) approved.