Atlas One · Host Biology · Scale 07 — System

Antiphospholipid Syndrome

Antiphospholipid syndrome (APS) is an autoimmune thrombophilia from anti-B2GPI and antiphospholipid antibodies; thrombosis (DVT, stroke) and obstetric morbidity; triple-positive aPL = highest risk. Indefinite anticoagulation (warfarin INR 2-3); LMWH + aspirin for obstetric APS.

Also known as: APS, antiphospholipid syndrome, Hughes syndrome, antiphospholipid antibody syndrome, APLS, catastrophic APS, CAPS, obstetric APS

Scale 07 — SystemScale
draftStatus
2026-06-07Last Reviewed
This is an auto-generated stub page built from atlas entry frontmatter. A richer hand-crafted page is planned. See the atlas source for the full entry including detailed body sections.
antiphospholipid-syndrome

Antiphospholipid Syndrome

Antiphospholipid syndrome (APS) is an autoimmune thrombophilia from anti-B2GPI and antiphospholipid antibodies; thrombosis (DVT, stroke) and obstetric morbidity; triple-positive aPL = highest risk. Indefinite anticoagulation (warfarin INR 2-3); LMWH + aspirin for obstetric APS.

Entry Metadata

FieldValue
IDantiphospholipid-syndrome
NameAntiphospholipid Syndrome
Statusdraft
Last reviewed2026-06-07
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toBeta2 Glycoprotein 1 connects-toImmunoglobulin G connects-toComplement C5 connects-toSystemic Lupus Erythematosus connects-toVenous Thromboembolism connects-toInherited Thrombophilia connects-toEndothelial Cell connects-toStroke connects-toPlacenta connects-toHeparin Induced Thrombocytopenia connects-toPlatelet connects-toHeart connects-toDisseminated Intravascular Coagulation connects-toImmune Thrombocytopenia connects-toSjogrens Syndrome connects-toThrombotic Thrombocytopenic Purpura connects-toAtherosclerosis connects-toMigraine connects-toThrombin connects-toB Cell connects-toReproductive System connects-toSkin connects-toKidney connects-toNeutrophil connects-toGlomerulus connects-toComplement C3 connects-toT Helper Cell connects-toCalcium connects-toBrain connects-toLung connects-toAdrenal Gland connects-toOxygen connects-toPlasma Cell connects-toPhoton connects-toLiver connects-toMtor connects-toElectron connects-toEye connects-toSpleen connects-toAntibody connects-toNeuron connects-toErythrocyte connects-toMusculoskeletal System connects-toCardiomyocyte connects-toLarge Intestine connects-toProtein C connects-toMacrophage connects-toPulmonary Arterial Hypertension connects-toTlr4 connects-toHeart Failure connects-toAhus connects-toNf Kb connects-toCkd connects-toEpilepsy connects-toSepsis connects-toMajor Depressive Disorder connects-toOvarian Cancer connects-toAlzheimers Disease connects-toMultiple Sclerosis connects-toWound Healing connects-toDigestive System connects-toNervous System connects-toGeneralized Anxiety Disorder connects-toImmune System connects-toIntegumentary System connects-toCardiovascular System connects-toRenal System connects-toRespiratory System connects-toEndocrine System connects-toWarfarin connects-toAspirin connects-toEpstein Barr Virus connects-toArterial Wall connects-toTargeted Therapy connects-toEndocardium connects-toAlveolus connects-toCovid 19 Disease connects-toHepatic Lobule connects-toMyocardium connects-toGerminal Center connects-toNmo connects-toPolycythemia Vera connects-toCortical Bone connects-toSystemic Sclerosis connects-toVon Willebrand Factor connects-toNitric Oxide connects-toFibrinogen connects-toS100A8 A9 connects-toPf4 connects-toEndothelin 1 connects-toC5Ar1 connects-toCcl2 connects-toVegf connects-toBaff connects-toCaspase 3 connects-toMhc Class Ii connects-toAkt connects-toTnf Alpha connects-toNlrp3 Inflammasome connects-toMyd88 connects-toSerotonin connects-toThrombopoietin connects-toErk1 2 connects-toPik3Ca connects-toGalectin 3 connects-toStat3 connects-toCgas Sting connects-toSmad4 connects-toJak1 2 connects-toStat1 connects-toFoxo connects-toGsk 3B connects-toSrc Kinase connects-toHif 1Alpha connects-toAmpk connects-toAutophagy connects-toCcr5 connects-toDnmt3A connects-toCxcl12 connects-toIl 1B connects-toIl 33 connects-toIl 17A connects-toCalcineurin connects-toCd20 connects-toIl 2 connects-toBcl 2 connects-toEstrogen connects-toTroponin Complex connects-toHemoglobin connects-toAdamts13 connects-toProstaglandins connects-toXanthine Oxidase connects-toIl 4 connects-toIl 13 connects-toZinc connects-toType I Interferon connects-toPd 1 connects-toCtla 4 connects-toLeptin connects-toAdiponectin connects-toResistin connects-toNatural Killer Cell connects-toIfn Gamma connects-toIl 12 connects-toIl 5 connects-toIl 23 connects-toIge connects-toFactor H connects-toC1 Esterase Inhibitor connects-toDendritic Cell connects-toOsteopontin connects-toTransferrin connects-toT Cytotoxic Cell connects-toTslp connects-toBradykinin connects-toErythropoietin connects-toHistamine connects-toPeriostin connects-toMelatonin connects-toTestosterone connects-toProlactin connects-toOxytocin connects-toVasopressin connects-toSelenium connects-toIodine connects-toSodium connects-toPotassium connects-toMagnesium connects-toCopper connects-toIron connects-toPhosphorus connects-toNitrogen connects-toCarbon connects-toChloride connects-toHydrogen connects-toSulfur connects-toGlp 1 connects-toAngiotensin Ii connects-toWnt Beta Catenin connects-toRankl connects-toFibronectin connects-toNotch connects-toIgf 1 connects-toActivin A connects-toTgf Beta connects-toCgrp connects-toCalcitonin connects-toSubstance P connects-toInsulin Receptor connects-toAldosterone connects-toAndrogen Receptor connects-toNorepinephrine connects-toAdrenomedullin