Atlas One · Host Biology · Scale 07 — System

Antiphospholipid Syndrome

Antiphospholipid syndrome (APS) is an autoimmune thrombophilia from anti-B2GPI and antiphospholipid antibodies; thrombosis (DVT, stroke) and obstetric morbidity; triple-positive aPL = highest risk. Indefinite anticoagulation (warfarin INR 2-3); LMWH + aspirin for obstetric APS.

Also known as: APS, antiphospholipid syndrome, Hughes syndrome, antiphospholipid antibody syndrome, APLS, catastrophic APS, CAPS, obstetric APS

Scale 07 — SystemScale
draftStatus
2026-06-07Last Reviewed
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antiphospholipid-syndrome

Antiphospholipid Syndrome

Antiphospholipid syndrome (APS) is an autoimmune thrombophilia from anti-B2GPI and antiphospholipid antibodies; thrombosis (DVT, stroke) and obstetric morbidity; triple-positive aPL = highest risk. Indefinite anticoagulation (warfarin INR 2-3); LMWH + aspirin for obstetric APS.