Atlas One · Host Biology · Scale 03 — Molecular

Beta-2 Glycoprotein I

Beta-2 glycoprotein I (B2GPI; APOH; chr17q24.2) is a plasma phospholipid-binding glycoprotein; domain I contains the dominant anti-B2GPI IgG epitope in APS; anti-B2GPI IgG activates endothelium, platelets, and complement → thrombosis and pregnancy loss.

Also known as: B2GPI, beta-2 glycoprotein I, APOH, apolipoprotein H, anti-B2GPI, antiphospholipid antigen, beta2-glycoprotein 1

Scale 03 — MolecularScale
draftStatus
2026-06-07Last Reviewed
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beta2-glycoprotein-1

Beta-2 Glycoprotein I

Beta-2 glycoprotein I (B2GPI; APOH; chr17q24.2) is a plasma phospholipid-binding glycoprotein; domain I contains the dominant anti-B2GPI IgG epitope in APS; anti-B2GPI IgG activates endothelium, platelets, and complement → thrombosis and pregnancy loss.

Entry Metadata

FieldValue
IDbeta2-glycoprotein-1
NameBeta-2 Glycoprotein I
Statusdraft
Last reviewed2026-06-07
Atlas01-human
Scale03-molecular

Cross-Atlas Connections

connects-toAntiphospholipid Syndrome connects-toImmunoglobulin G connects-toComplement C5 connects-toSystemic Lupus Erythematosus

Sources