Atlas One · Host Biology · Scale 03 — Molecular

Von Willebrand Factor

Von Willebrand factor (VWF; chr12p13.3) is a plasma glycoprotein that bridges platelet GPIb to subendothelial collagen at sites of injury; carries FVIII in circulation; deficiency → VWD; ULVWF → TTP. Emicizumab bridges FIXa/FX bypassing FVIII in hemophilia A.

Also known as: VWF, von Willebrand factor, vWF, VWD antigen, factor VIII carrier, ULVWF, ultra-large von Willebrand factor, vWF multimers

Scale 03 — MolecularScale
draftStatus
2026-06-07Last Reviewed
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von-willebrand-factor

Von Willebrand Factor

Von Willebrand factor (VWF; chr12p13.3) is a plasma glycoprotein that bridges platelet GPIb to subendothelial collagen at sites of injury; carries FVIII in circulation; deficiency → VWD; ULVWF → TTP. Emicizumab bridges FIXa/FX bypassing FVIII in hemophilia A.

Entry Metadata

FieldValue
IDvon-willebrand-factor
NameVon Willebrand Factor
Statusdraft
Last reviewed2026-06-07
Atlas01-human
Scale03-molecular

Cross-Atlas Connections

connects-toAdamts13 connects-toThrombotic Thrombocytopenic Purpura connects-toHemophilia A connects-toVenous Thromboembolism connects-toPlatelet connects-toFibrinogen connects-toThrombin

Sources