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attention-deficit-hyperactivity-disorder
Attention-Deficit/Hyperactivity Disorder
ADHD (5-10% prevalence; 4:1 male:female) is driven by prefrontal cortex dopamine/norepinephrine deficiency impairing executive function; stimulants (methylphenidate, amphetamines) are first-line; 60-70% of childhood ADHD persists into adulthood.
Entry Metadata
| Field | Value |
|---|---|
| ID | attention-deficit-hyperactivity-disorder |
| Name | Attention-Deficit/Hyperactivity Disorder |
| Status | draft |
| Last reviewed | 2026-06-08 |
| Atlas | 01-human |
| Scale | 07-system |
Cross-Atlas Connections
Sources
- Faraone SV, Banaschewski T, Coghill D, et al. The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder. Neurosci Biobehav Rev. 2021;128:789-818. · PubMed 33549739
- Arnsten AF. Toward a new understanding of attention-deficit hyperactivity disorder pathophysiology: an important role for prefrontal cortex dysfunction. CNS Drugs. 2009;23(Suppl 1):33-41. · PubMed 19621976
- Biederman J, Faraone SV. Attention-deficit hyperactivity disorder. Lancet. 2005;366(9481):237-248. · PubMed 16023516