Atlas One · Host Biology · Scale 07 — System

Anorexia Nervosa

Anorexia nervosa (0.9% female lifetime; highest mortality of any psychiatric disorder ~5-10%/decade) involves reward circuit dysregulation, leptin deficiency, cortisol excess, and 5-HT dysregulation; only evidence-based treatment: nutritional rehabilitation + FBT or CBT-E.

Also known as: anorexia nervosa, AN, anorexia, restrictive AN, purging AN, EDE-Q, EDE, FBT, CBT-E, ARFID, refeeding syndrome, amenorrhea, weight restoration

Scale 07 — SystemScale
draftStatus
2026-06-08Last Reviewed
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anorexia-nervosa

Anorexia Nervosa

Anorexia nervosa (0.9% female lifetime; highest mortality of any psychiatric disorder ~5-10%/decade) involves reward circuit dysregulation, leptin deficiency, cortisol excess, and 5-HT dysregulation; only evidence-based treatment: nutritional rehabilitation + FBT or CBT-E.

Entry Metadata

FieldValue
IDanorexia-nervosa
NameAnorexia Nervosa
Statusdraft
Last reviewed2026-06-08
Atlas01-human
Scale07-system

Cross-Atlas Connections

connects-toSerotonin connects-toDopamine connects-toLeptin connects-toCortisol connects-toBdnf targetsBrain connects-toBinge Eating Disorder connects-toHeart connects-toBone Marrow connects-toBulimia Nervosa connects-toOsteoporosis connects-toObsessive Compulsive Disorder

Sources