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growth-hormone
Growth Hormone
22 kDa pituitary somatotroph hormone regulated by GHRH and somatostatin; drives hepatic IGF-1 (JAK2/STAT5b), growth, muscle anabolism, and lipolysis; acromegaly from GH-secreting adenoma; GH deficiency causes growth failure and metabolic syndrome.
Entry Metadata
| Field | Value |
|---|---|
| ID | growth-hormone |
| Name | Growth Hormone |
| Status | draft |
| Last reviewed | 2026-06-08 |
| Atlas | 01-human |
| Scale | 03-molecular |
Cross-Atlas Connections
Sources
- Melmed S. Acromegaly pathogenesis and treatment. J Clin Invest. 2009;119(11):3189-3202. · PubMed 19884662
- Van Cauter E, Plat L, Scharf MB, et al. Simultaneous stimulation of slow-wave sleep and growth hormone secretion by gamma-hydroxybutyrate in normal young men. J Clin Invest. 1997;100(3):745-753. · PubMed 9239424
- Jørgensen JO, Pedersen SA, Thuesen L, et al. Beneficial effects of growth hormone treatment in GH-deficient adults. Lancet. 1989;1(8649):1221-1225. · PubMed 2566796